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Synthesis and trafficking of the tonoplast potassium channel AtTPK1
(1) Istituto di Biologia e Biotecnologia Agraria, Consiglio Nazionale delle Ricerche, Milan, Italy (2) Institut fur Biochemie und Biologie, Universitaet Potsdam, Potsdam-Golm, Germany
Sorting signals of tonoplast proteins and the pathway they follow through the endomembrane system are still poorly characterized. Using Brefeldin A (an inhibitor of the Golgi-mediated traffic) we showed that a Golgi-dependent pathway for tonoplast delivery may exist. Then we generated various chimeric TPK1-TPK4 fusions, exchanging various domains. We observed that the cytosolic, C-terminal domain of TPK1 is sufficient to re-direct the plasma membrane TPK4 to the tonoplast.
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Anti-inflammatory activity of Dalbergia sissoo Roxb. heart-wood
L. M. College of Pharmacy
The heart-wood of Dalbergia sissoo Roxb. is reported to be used in traditional medicinal practices, of which anti-inflammatory is one. The present work evaluates the effect of the heart-wood extract on the carrageenan induced rat paw edema. The drug was found to be active at lowest of 3 doses tried. the drug can be said to posses anti-inflamatory activity but needs further evaluation of discover the pathway of the same.
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Postdoctoral Research Associate
Northeastern University
The Center for Drug Discovery at Northeastern University is dedicated to designing and discovering novel medications, developing technologies, and training scientists in the multidisciplinary field of drug discovery. We are recruiting a Postdoctoral Research Associate with expertise in protein-based mass spectrometry and /or proteomics.
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Product Manager - Techne, Stone, Staffordshire
Bibby Scientific
Bibby Scientific Ltd is one of the world’s leading manufacturers of Laboratory bench-top scientific equipment. For more information about the company, please visit their website (www.bibby-scientific.com).
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Assistant/Associate Professors
Chinese University of Hong Kong
The newly established School of Biomedical Sciences, Stem Cell and Regeneration theme is actively looking for stem cell biologist over the next 2 years.
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Macromolecular X-ray Crystallgrapher
Xtal Biostructures
Ph.D. Protein Crystallographer: We seek an experienced crystallographer with post-doctoral experience to participate in a number of our diverse structural biology activities.
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Marketing Communications Specialist Position in San Jose, CA
Thermo Fisher Scientific
This position, based in San Jose, CA within the SID Division, will manage promotion of Thermo Scientific mass spectrometry products and services.
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St. Jude Children's Research Hospital has an opening for a Senior Research Technologist (Job Number 18046)
St Judes Research Hospital
St. Jude Children's Research Hospital, located in Memphis, Tennessee, is a premier center for research and treatment of potentially fatal childhood diseases, including cancer and certain blood, genetic, and immunodeficiency disorders. The hospital's mission is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment.
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PITTCON Conference & Exposition 2010, Orlando, Florida
28 February 2010 - 05 March 2010
Pittcon 2010, the world’s largest annual conference and exposition for laboratory science. Pittcon offers the latest innovations from nearly 1,000 exhibitors, unique networking opportunities with world renowned scientists and exceptional educational opportunities.
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Advances in Synthetic Chemistry
08 April 2010 - 09 April 2010
The 3rd annual Advances in Synthetic Biology aims to cover the following topics: The Chemistry of Synthetic Biology; Protein, Metabolic & Therapeutic Engineering; Bioinformatics and Software Modelling in Synthetic Biology; Cell & Tissue Engineering and The Road Towards the Rational and Systemic Design of Novel Biological Systems.
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MedChem Europe
08 April 2010 - 09 April 2010
Due to its continuing success, Select Biosciences is very pleased to announce their 7th MedChem Europe conference and exhibition. For 2010 the meeting will be co-located with Advances in Synthetic Chemistry, ADMET Europe and Pharma Outsourcing Congress. Topics such as Compound Management; Chemogenomics; Fragment Based Lead Detection and Formulation will be discussed.
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Cleaning Microreactors
Syrris Ltd
This application note gives hints and tips on cleaning & unblocking flow reactors, i.e. chips or tube based reactors. It is suggested that the whole document is read before attempting to unblock a reactor.
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